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COVID-19 and HIV/AIDS in a cohort study in Sao Paulo, Brazil: outcomes and disparities by race and schooling
June 4, 2021
S Q Rocha, V I Avelino-Silva M V Tancredi, L F Jamal, P R A Ferreira, A Tayra, P M Ferreira, T Carvalhanas, C S B Domingues, R A Souza, M C Gianna, A O Kalichman, O H M Leite, T N L Souza, D A Gomes E Costa, J J D Furtado, A F Costa, HIV-COVID/SP Study Group.
AIDS Care
Rocha et al.’s retrospective cohort study aimed to identify the impacts of age, race, and schooling on COVID-19 outcomes for people living with HIV/AIDS (PLHIV). Lab-confirmed SARS-CoV-2 cases in Sao Paulo, Brazil between March and June of 2020 were crossed checked with national HIV surveillance to determine HIV status. Predictor variables selected from SARS reporting forms and HIV surveillance systems included race, age groupings, and years of schooling. The study found no statistically significant association between predictors and ICU admission; however, the mortality rate for PLHIV with COVID-19 was 4.1 per 1,000 person-days with a 34% case-fatality rate. Higher mortality rates were specifically found among patients older than 60, Black/Mixed patients, and those with less than 8 years of schooling. The study did not find statistically significant associations between tenofovir use and ICU admission or mortality in patients under anti-retroviral therapy.
Rocha SQ, Avelino-Silva VI, Tancredi M V., et al. COVID-19 and HIV/AIDS in a cohort study in Sao Paulo, Brazil: outcomes and disparities by race and schooling. AIDS Care 2021; 1–7.
