A population study evaluated the influence of masks on the properties of the skin, 20 people were included, of Korean nationality without history of dermatological pathologies, specifically 11 men and 9 women, who could use masks for 6 hours in 2 weeks measured eight biophysical skin parameters namely temperature, redness, pore volume, texture, elasticity, TEWL, sebum content and pH, multiple devices using non-invasive methods. Results showed an increase in skin temperature (2.09°C), transdermal water loss (8.57%), sebum (135.49%), pore volumes (73.16%) and the mean count of acne lesions (1.65), accompanied by a decrease in pH (3.24%) and skin elasticity (7.12%-9.90%), the differences regarding sex were showed in the rate of change of skin elasticity, which was 0.03% in men, resulted in 6.62% in women after 6 hours of mask use.