.svg){kind=small}
Clinically Suspected Myocarditis Temporally Related to COVID-19 Vaccination in Adolescents and Young Adults: Suspected Myocarditis After COVID-19 Vaccination
February 1, 2022
Truong et al., 2022
Circulation AHA
Of 139 adolescents and young adults with 140 episodes of suspected myocarditis at 26 centers. Most patients were male (n=126, 90.6%) and White (n=92, 66.2%); 29 (20.9%) were Hispanic; and the median age was 15.8 years (range, 12.1-20.3; interquartile range [IQR], 14.5-17.0). Suspected myocarditis occurred in 136 patients (97.8%) after the mRNA vaccine, with 131 (94.2%) after the Pfizer-BioNTech vaccine; 128 (91.4%) occurred after the second dose. Symptoms started at a median of 2 days (range, 0-22; IQR, 1-3) after vaccination. Most cases of suspected COVID-19 vaccine myocarditis occurring in persons <21 years have a mild clinical course with rapid resolution of symptoms. Abnormal findings on cardiac MRI were frequent. Future studies should evaluate risk factors, mechanisms, and long-term outcomes.
Truong, D. T., Dionne, A., Muniz, J. C., McHugh, K. E., Portman, M. A., Lambert, L. M., Thacker, D., Elias, M. D., Li, J. S., Toro-Salazar, O. H., Anderson, B. R., Atz, A. M., Bohun, C. M., Campbell, M. J., Chrisant, M., D’Addese, L., Dummer, K. B., Forsha, D., Frank, L. H., & Frosch, O. H. (2022). Clinically Suspected Myocarditis Temporally Related to COVID-19 Vaccination in Adolescents and Young Adults: Suspected Myocarditis After COVID-19 Vaccination. Circulation, 145(5), 345–356. https://doi.org/10.1161/circulationaha.121.056583
