The authors surveyed 174 undergraduate, masters, and doctoral nursing students in Los Angeles to examine the relationship between stressful COVID-19 experiences and mental health for those in the nursing profession. In addition to a survey asking participants to summarize their experiences with COVID-19, the Patient Health Questionnaire (PHQ-2) was used to screen for depression, the General Anxiety Disorder-7 (GAD-7) was used to measure anxiety. Loneliness was assessed using the DeJong Gierveld Loneliness scale and resiliece was measured using the Brief Resilience Scale. Despite only 7.5% of respondents reporting having tested positive for COVID-19, 30% of respondents had high levels of depression and COVID-19-related traumatic stress. 38% of respondents reported high anxiety. Respondents with higher loneliness scores demonstrated higher odds of depression (OR = 1.64; 95% CI [1.24, 2.16]) and anxiety (OR = 1.40, 95% CI [1.10, 1.78]) attributed to COVID-19. Lower odds of depression were seen with higher resilience scores. However, the authors found no significant relationship between stressful COVID-19 experiences and mental health need.