Susceptibility of raccoon dogs for experimental SARS-CoV-2 infection

November 18, 2020

Freuling CM, Breithaupt A, Müller T, et al.

Emerging Infectious Diseases

The goal of this study was to characterize viral shedding, transmission potential, susceptibility, serologic reactions, and pathologic lesions of raccoon dogs after experimental SARS-CoV-2 infection. Nine naive raccoon dogs were intranasally inoculated with 10^5 50% tissue culture infectious dose (TCID50) SARS-CoV-2 2019_nCoV Muc-IMB-1. Direct transmission was tested 24 hours after inoculation with 3 naiveanimals. Three animals were lethargic four days after inoculation and none of the exposedor contact animals had fever, weight loss, or other signs of infection. Of the nineinoculated animals, six had viral shedding. Infection was detected in two of the threecontact animals. Viral replication and tissue lesions were only found in the nasal conchae.The study demonstrates that raccoon dogs are susceptible to SARS-CoV-2 infection andcan transmit the virus to direct in-contact animals. Authors suggest that additionalsurveillance is needed on susceptible animals such as raccoon dogs in China since thecountry is a large source of global fur production.

FreulingCM,BreithauptA,MüllerT,etal.SusceptibilityofRaccoonDogsfor Experimental SARS-CoV-2 Infection. Emerg Infect Dis 2020; 26.

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